The Scenarionist - Deep Tech Startups & Venture Capital | Substack

When Niche Beats Scale: How Top-Tier Deep Tech Startups Thrive in Unsexy Markets

Power Laws and the Hidden Edge of Niche Dominance: 3 Real-World Case Studies

Jul 12 •

Giulia Spano, PhD

Beyond the AI Bubble. AI Goes Vertical. AI Goes Industrial.

Capital Intensity Defines the Platform Race; Defensibility Defines the Vertical One.

Sep 11 •

Giulia Spano, PhD

💸 $100M AI Molecule Search Engine; $58M to Scale Optical Chips; €200M to Accelerate Stellarator Hardware; $6M to Scale Industrial…

The Weekly Observer of Deep Tech Capital Markets: where the money moves, who drives it, and why it matters.

6 hrs ago

Sodium-Ion’s Working-Capital Trap: What Natron’s Wind-Down Teaches About Financing New Chemistries | Deep Tech Briefing Vol. 78

Weekly Intelligence on Deep Tech Private Market.

Sep 14 •

Nicola Marchese & Giulia Spano

24:24

Food Tech from Lab to Market: Strategy, Roadmap, and Traction | Deep Tech Catalyst

Watch now | A chat with Amira Khatib, Vice President @ Bluestein Ventures

Sep 12 •

Nicola Marchese, MD

DeepTech Catalyst

24:24

Food Tech from Lab to Market: Strategy, Roadmap, and Traction | Deep Tech Catalyst

Watch now | A chat with Amira Khatib, Vice President @ Bluestein Ventures

Sep 12 •

Nicola Marchese, MD

Insights

Beyond the AI Bubble. AI Goes Vertical. AI Goes Industrial.

Capital Intensity Defines the Platform Race; Defensibility Defines the Vertical One.

Sep 11 •

Giulia Spano, PhD

AI ≠ SaaS: the Metrics Reset.

Why Continuous Calibration/Continuous Development (CC/CD) Redefines Scalability and Risk in AI Startups.

Aug 28 •

Giulia Spano, PhD

Deep Tech Investment Secrets: What Top VCs Do Differently - Part 2

Designing scarcity, mapping risk, and replacing TAM theater with real buyer-backed growth models.

Aug 21

Deep Tech Investment Secrets: What Top VCs Do Differently - Part 1

Strategic patterns used by leading deep tech investors to get better deals, faster access, and lower downstream risk.

Aug 14

The Power Law of Matter: Why Advanced Materials are Eating Digital Margins

From SaaS Logic to Commodity Logic. From advanced materials in photonics to fusion energy — the real profit pools are moving back into the atomic layer.

Jul 24

When Niche Beats Scale: How Top-Tier Deep Tech Startups Thrive in Unsexy Markets

Power Laws and the Hidden Edge of Niche Dominance: 3 Real-World Case Studies

Jul 12 •

Giulia Spano, PhD

Reverse Diligence: How Three Advanced Energy Materials Companies Beat the Scaling Bottleneck

Amprius, Nexeon & Enovix: A reverse DD analysis of three real-world scale-ups on moats, capital discipline, and scaling advanced materials for…

Jul 3

Pre-Revenue Valuation in Deep Tech: How to Price What Doesn’t Exist Yet — Part 2

Valuation in Action: Deep Tech Startups and Real-World Case Studies

Jun 19

Capital Movements

💸 $100M AI Molecule Search Engine; $58M to Scale Optical Chips; €200M to Accelerate Stellarator Hardware; $6M to Scale Industrial…

The Weekly Observer of Deep Tech Capital Markets: where the money moves, who drives it, and why it matters.

6 hrs ago

💸 $44M Logistics Agents; $34M Quantum Algorithms; $22M Farm Vision AI; $15M Zinc-Bromine Storage; $14M Plant-Protein Polymers & more …

The Weekly Observer of Deep Tech Capital: where the money moves, who drives it, and why it matters.

Sep 8 •

Giulia Spano, PhD

💸 $863M Fusion Plant; $50M Maritime Autonomy; $28M Battery Induction; $12.4M Virtual Megawatts; €5.5M Deep Geothermal & more | Capital…

The Weekly Observer of Deep-Tech Capital: where the money moves, who drives it, and why it matters.

Sep 1 •

Giulia Spano, PhD

💸 $405M Robot Brains; $463M EV Anodes; $275M GPU Credit; $313M Gene Therapy; $230M Corporate Security; $100M Nuclear for AI | Capital…

The Week’s State of Deep Tech Capital: who’s Raising, who’s Betting, and why.

Aug 25 •

Giulia Spano, PhD

VC Guides

28:55

Investing in Mining Tech: Scalable Models, Case Studies, And Due Diligence

From AI-Driven Discovery to Critical Mineral Supply Chains | Jason Holt, Partner @ Orion Industrial Ventures

Jun 5 •

Nicola Marchese, MD

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